MSC offers a flexible software-based workflow that covers all stages of research and development of TOF instruments.
From instrument tuning to mass spectrometry applications
MSC FastControl software provides flexible and safe control of TOF MS power electronic units as well as synchronized programmable control of fast separation devices like quadrupoles, collision cells, ion mobility separators, etc.
MSC AutoTune
Provides automated tuning of key units of TOF instruments like mass analyzers, ion optical interface, detectors. A set of tools facilitate development of automated scenarios for factory- and daily tuning procedures.
MCH Data Format
- Highly-efficient lossless compressed data format for time-of-flight data
- High compression ratio achieved through the effective use of TOF data features
- Multi-layer structure to handle various combinations of LC(GC)/MS, LC/MS/MS, LC/IMS/MS datasets
- API to access MCH files from third-party software
- Converters to/from mzML data format
TOF Acquisor
A modular software suite to handle research-grade data acquisition at TOF MS instruments
- Real-time data processing core utilizes full power of multi-core CPUs and (optionally) GPU
- Internal driver modules supports digitizers by Acqiris, Teledyne and other manufacturers
- Advanced display of acquired data with tracking of a set of TOF signal metrics facilitates manual and automated tuning of mass analyzers and other instrumental units
- Supports integration with TOF Sequencer and third-party instrument control software to provide automated sample measurements
Data Analysis & Visualization
A key part of MSC software technology is a set of dedicated tools for engineering-level visual display of TOF signals, data processing and in-depth analysis, including:
- Calibration of mass-to-charge scale
- Calibration of spectrum intensity by a single ion response
- Peak finding, feature extraction and deconvolution
- Extraction of analytical parameters of TOF peaks
- Tracking of signal parameters in time
- Calculation of metrics of peak shape and TOF spectrum distortion;
- A set of internal tools characterizing dynamic range, mass tolerance, verification of isotope abundance ratios and many others.
Simulation & Statistical Analysis
Development of TOF MS instruments requires keeping track of instrument performance in a wide range of analytical parameters by comparing MS data against reference datasets. To implement this approach, MSC developed a set of software tools for simulation of MS, LC/MS and MS/MS signals.
MSC SW tools for statistical analysis make possible verification of TOF MS analytical parameters like LOD, dynamic range, mass accuracy on MS, LC/MS and LS/MS/MS data from real-life proteomic samples.
